Commentary on ‘Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma’
نویسندگان
چکیده
منابع مشابه
Nedocromil sodium in adults with asthma dependent on inhaled corticosteroids: a double blind, placebo controlled study.
Eighty nine adults with asthma who were receiving inhaled corticosteroid and bronchodilator treatment took part in a double blind, randomised, placebo controlled trial of nedocromil sodium, 4 mg four times daily by inhalation. During a run in period of two to four weeks corticosteroid treatment was reduced when possible to produce a comparable level of symptoms across the trial population. The ...
متن کاملInhaled corticosteroids in children with persistent asthma: effects on growth.
BACKGROUND Treatment guidelines for asthma recommend inhaled corticosteroids (ICS) as first-line therapy for children with persistent asthma. Although ICS treatment is generally considered safe in children, the potential systemic adverse effects related to regular use of these drugs have been and continue to be a matter of concern, especially the effects on linear growth. OBJECTIVES To assess...
متن کاملInhaled corticosteroids and long term outcome in adults with asthma.
The concept that treatment with inhaled corticosteroids (ICS) may improve long term lung function by reversing or minimising the effects of airway remodelling remains an attractive one but, until now, unproven. It is therefore with much interest that we read the publications of two observational studies by Lange et al and by Dijkstra et al. Both groups of authors hypothesised that asthmatic ind...
متن کاملLong-acting beta2-agonists versus placebo in addition to inhaled corticosteroids in children and adults with chronic asthma.
BACKGROUND Long-acting inhaled beta2-adrenergic agonists are recommended as 'add-on' medication to inhaled corticosteroids in the maintenance therapy of asthmatic adults and children aged two years and above. OBJECTIVES To quantify in asthmatic patients the safety and efficacy of the addition of long-acting beta2-agonists to inhaled corticosteroids on the incidence of asthma exacerbations, pu...
متن کاملSodium cromoglycate in nocturnal asthma.
To investigate whether mast cell degranulation was important in producing nocturnal asthma, the effect of a single high dose of nebulised sodium cromoglycate on overnight bronchoconstriction, oxygen saturation, and breathing patterns in eight patients with nocturnal wheeze was examined. The study took the form of a double blind placebo controlled crossover comparison. Treatment with cromoglycat...
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ژورنال
عنوان ژورنال: Evidence-Based Child Health: A Cochrane Review Journal
سال: 2006
ISSN: 1557-6272,1557-6272
DOI: 10.1002/ebch.81